Analytical-grade documentation for research compounds.

Selank vs Benzodiazepines: What the Russian Head-to-Head Trials Actually Compared

Selank is a heptapeptide anxiolytic registered in the Russian Federation for generalized anxiety disorder. The Russian-language clinical literature contains direct comparisons against classical benzodiazepines. This article walks through the mechanism, the head-to-head trials (Zozulya 2008, Volkova 2016), the divergent side-effect profile, and the structural limitations of the evidence base — without pretending the comparison is settled in Western journals.

May 27, 202611 min read

Methods & Quality

Analytical methods, accreditation, and how purity is verified.

Endotoxin Testing Explained: USP <85> and Why It Matters for Reconstituted Peptides

Bacterial endotoxin testing is the contamination dimension HPLC purity cannot see. A reading guide to USP <85> and the new USP <86> (recombinant Factor C) — the three LAL methods, the K/M endotoxin-limit calculation, and why the diluent on a reconstituted peptide vial is half the story.

May 3, 202612 min read

How We Verify Peptide Purity: HPLC, Mass Spec, and ISO 17025

A walkthrough of the analytical methods PepMax requires for every lot — what each technique measures, why we use accredited third-party labs, and how the results land in the COA you receive.

Apr 30, 202611 min read

How to Read a Peptide Certificate of Analysis

A field-by-field reading guide for the certificate of analysis that ships with a research peptide — what every line means, the five fields most stores quietly omit, and the chromatogram and mass-spectrum tells that separate a real COA from a dressed-up summary.

Apr 30, 202613 min read

What ≥99% Purity Actually Means in Peptide Research

Most vendors print "≥99% purity" on every product page. The number is meaningful only with a lot-specific COA, a stated method, and an understanding of what HPLC purity does — and does not — measure.

Apr 29, 20269 min read

Compound Profiles

Mechanism, stability, and research context for individual compounds.

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Melanotan II: Compound Profile

A scientific profile of Melanotan II (MT-II) — a cyclic heptapeptide α-MSH analog developed at the University of Arizona in the late 1980s. Mechanism across MC1R / MC3R / MC4R / MC5R, the small early human trials in tanning and erectile function, the FDA-approved spinoff molecules (afamelanotide and bremelanotide), and an honest accounting of the safety case reports and the regulatory warnings that surround unregulated use.

May 12, 202612 min read

TB-500 (Thymosin β4): Compound Profile

A scientific profile of TB-500 — the synthetic 43-residue thymosin β4 peptide. Sequence, the G-actin–sequestering mechanism that anchors its biology, the published Phase 1–3 evidence in cardiac, dermal, and ocular indications, and the place of its N-terminal cleavage product Ac-SDKP. An honest accounting of where the human data does and does not exist.

May 3, 202614 min read

Tesamorelin (Egrifta): Compound Profile

A scientific profile of tesamorelin (TH9507) — a synthetic 44-amino-acid GHRH analog and the only FDA-approved peptide in the PepMax catalog. Mechanism, the pivotal Phase 3 trials in HIV-associated lipodystrophy, the Lancet HIV NAFLD trial, the Egrifta / Egrifta SV / Egrifta WR formulation history, and the constraints that govern off-label use.

May 3, 202613 min read

What Recent Trials Show About Retatrutide (LY3437943)

A reading list of the major published retatrutide trials — the discovery paper, Phase 1 in type 2 diabetes, the Phase 2 obesity and diabetes studies, the MASLD substudy, and the TRIUMPH Phase 3 program. What each study measured, what it reported, and what it does and does not establish.

Apr 30, 202613 min read

Comparisons

Side-by-side analysis of related compounds and methodologies.

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Selank vs Benzodiazepines: What the Russian Head-to-Head Trials Actually Compared

May 27, 202611 min read

NAD+, NMN, and NR: What the Human Clinical Trials Actually Show

A structured reading list of human clinical trials on NAD+ and its precursors — nicotinamide riboside (NR), nicotinamide mononucleotide (NMN), nicotinamide (NAM), nicotinic acid, and intravenous NAD+. Pharmacokinetics, the trials that established what each precursor does in human blood, the small set of trials that have moved past pharmacokinetics into clinical endpoints, and an honest accounting of where the longevity hypothesis sits in human evidence.

May 7, 202618 min read

BPC-157 vs TB-500: Mechanism, Evidence, and Combination Rationale

A side-by-side scientific comparison of pentadecapeptide BPC-157 and TB-500 (synthetic thymosin β4). Mechanism, sequence, evidence base, what each is FDA-, EMA-, and WADA-rated as, and an honest accounting of what is and is not supported by the literature about the popular practice of stacking them.

May 3, 202612 min read