Comparisons

Side-by-side analysis of related compounds and methodologies.

Selank vs Benzodiazepines: What the Russian Head-to-Head Trials Actually Compared

Selank is a heptapeptide anxiolytic registered in the Russian Federation for generalized anxiety disorder. The Russian-language clinical literature contains direct comparisons against classical benzodiazepines. This article walks through the mechanism, the head-to-head trials (Zozulya 2008, Volkova 2016), the divergent side-effect profile, and the structural limitations of the evidence base — without pretending the comparison is settled in Western journals.

May 27, 202611 min read

Comparisons

NAD+, NMN, and NR: What the Human Clinical Trials Actually Show

A structured reading list of human clinical trials on NAD+ and its precursors — nicotinamide riboside (NR), nicotinamide mononucleotide (NMN), nicotinamide (NAM), nicotinic acid, and intravenous NAD+. Pharmacokinetics, the trials that established what each precursor does in human blood, the small set of trials that have moved past pharmacokinetics into clinical endpoints, and an honest accounting of where the longevity hypothesis sits in human evidence.

May 7, 202618 min read

Comparisons

BPC-157 vs TB-500: Mechanism, Evidence, and Combination Rationale

A side-by-side scientific comparison of pentadecapeptide BPC-157 and TB-500 (synthetic thymosin β4). Mechanism, sequence, evidence base, what each is FDA-, EMA-, and WADA-rated as, and an honest accounting of what is and is not supported by the literature about the popular practice of stacking them.

May 3, 202612 min read

Comparisons

The GLP-1 Incretin Landscape: Approved and Late-Stage Therapeutics in 2026

A structured reading list of the modern incretin class — semaglutide, tirzepatide, retatrutide, CagriSema, survodutide, and orforglipron. Receptor pharmacology, the trials that established each compound, the headline weight and metabolic effects, and what each program does and does not yet establish.

Apr 30, 202617 min read

Comparisons

Semax vs Selank: A Comparison of Two Russian Heptapeptide Nootropics

Semax and Selank are both seven-residue synthetic peptides developed at the Russian Academy of Sciences in the 1990s and delivered intranasally in clinical research. They are routinely confused. This article separates them — sequence by sequence, mechanism by mechanism, indication by indication — and explains why one is investigated for cognitive activation and the other for anxiolysis without sedation.

Apr 29, 202611 min read

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