Compound Profiles

Mechanism, stability, and research context for individual compounds.

Melanotan II: Compound Profile

A scientific profile of Melanotan II (MT-II) — a cyclic heptapeptide α-MSH analog developed at the University of Arizona in the late 1980s. Mechanism across MC1R / MC3R / MC4R / MC5R, the small early human trials in tanning and erectile function, the FDA-approved spinoff molecules (afamelanotide and bremelanotide), and an honest accounting of the safety case reports and the regulatory warnings that surround unregulated use.

May 12, 202612 min read

Compound Profiles

TB-500 (Thymosin β4): Compound Profile

A scientific profile of TB-500 — the synthetic 43-residue thymosin β4 peptide. Sequence, the G-actin–sequestering mechanism that anchors its biology, the published Phase 1–3 evidence in cardiac, dermal, and ocular indications, and the place of its N-terminal cleavage product Ac-SDKP. An honest accounting of where the human data does and does not exist.

May 3, 202614 min read

Compound Profiles

Tesamorelin (Egrifta): Compound Profile

A scientific profile of tesamorelin (TH9507) — a synthetic 44-amino-acid GHRH analog and the only FDA-approved peptide in the PepMax catalog. Mechanism, the pivotal Phase 3 trials in HIV-associated lipodystrophy, the Lancet HIV NAFLD trial, the Egrifta / Egrifta SV / Egrifta WR formulation history, and the constraints that govern off-label use.

May 3, 202613 min read

Compound Profiles

What Recent Trials Show About Retatrutide (LY3437943)

A reading list of the major published retatrutide trials — the discovery paper, Phase 1 in type 2 diabetes, the Phase 2 obesity and diabetes studies, the MASLD substudy, and the TRIUMPH Phase 3 program. What each study measured, what it reported, and what it does and does not establish.

Apr 30, 202613 min read

Compound Profiles

BPC-157: Compound Profile

A scientific profile of pentadecapeptide BPC-157 (PL 14736) — sequence, proposed mechanisms, the preclinical evidence base across tendon, gastrointestinal, vascular, and central nervous system models, and an honest accounting of where human data does and does not exist.

Apr 30, 202614 min read

Compound Profiles

GHK-Cu: Compound Profile

A scientific profile of glycyl-L-histidyl-L-lysine copper(II) — sequence, copper coordination chemistry, the gene-expression and tissue-remodeling literature, the human topical and chronic-wound trials that exist, and an honest accounting of what fifty years of research does and does not establish.

Apr 30, 202614 min read

Compound Profiles

MOTS-c: Compound Profile

A scientific profile of MOTS-c — the 16-amino-acid peptide encoded inside the mitochondrial 12S rRNA gene. Origin in the mitochondrial genome, the AMPK and folate-cycle mechanism, the nuclear-translocation retrograde-signaling story, the exercise and aging human-observational data, the discontinued CohBar CB4211 clinical program, and an honest accounting of what a decade of research does and does not establish.

Apr 30, 202613 min read

FOR RESEARCH USE ONLY

This product is sold for in vitro laboratory research purposes only. Not a drug, supplement, or household product. Not intended for human consumption, therapeutic use, or veterinary use. Read the full disclaimer.